II. SYNTHESIS OF 1-NAPHTHOXY-3-SUTURATED AMINAPROPANOLES, WHICH CONTAIN FRAGMENT OF AMINOACIDS

Abstract

As a continuation of our investigations in the field of creation of potential (3-adrenoblokers, the method for realization of interaction of l,2-epoxy-3-naphthoxy-propane with some α- and β-aminoacids has been developed and proposed. In particular the aminoacids don’t react with epoxides, as they are in the form of internal salts. For the purpose of realization the interaction with some α- and β-aminoacids, they were transformed into their sodium salt, which easily interact with an epoxides according to Krasusky’s rule. As a result N-(naphthoxy-2-hydroxypropil) aminoacids were obtained.