MEMBRANOTROPIC EFFECT OF $MONTIVIPERA~RADDEI$ AND$ MACROVIPERA~LEBETINA~OBTUSA$ VENOM WITH PHOSPHOLIPASE A2 INHIBITED BY p-BROMOPHENACYL BROMIDE
DOI:
https://doi.org/10.46991/PYSU:B/2015.49.3.047Keywords:
GUV, $Macrovipera~lebetina~obtuse$, $Montivipera~raddei$,phospholipase A2, p-bromophenacyl bromideAbstract
In the article influence of Montivipera raddei and Macrovipera lebetina obtusa venom including phospholipase A2 (PLA2) inhibited by p-bromophenacyl bromide on giant unilamellar vesicles, visualized with 8-anilino-1-naphthalenesulfonic acid fluorescence probe, was investigated. The results have shown that both venoms even without the PLA2 activity have a noticeable membranotropic effect on the artificial membranes, but in different ways, so one can propose that investigated viper venoms can contain different PLA2 isomers.
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Published
2015-11-20
How to Cite
Ghulikyan, L.A. 2015. “MEMBRANOTROPIC EFFECT OF $MONTIVIPERA~RADDEI$ AND$ MACROVIPERA~LEBETINA~OBTUSA$ VENOM WITH PHOSPHOLIPASE A2 INHIBITED BY P-BROMOPHENACYL BROMIDE”. Proceedings of the YSU B: Chemical and Biological Sciences 49 (3 (238):47-52. https://doi.org/10.46991/PYSU:B/2015.49.3.047.
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Biology
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