EVALUATION OF BINDING PARAMETERS OF INTERCALATORS METHYLENE BLUE, ETHIDIUM BROMIDE AND ACRIDINE ORANGE WITH NUCLEIC ACIDS

Authors

  • V.G. Sahakyan Chair of Biophysics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2017.51.3.176

Keywords:

DNA, binding strong mode, weak mode, binding parameters

Abstract

Comparison of values of the binding constant (K) and number of binding sites (n) of methylene blue, ethidium bromide and acridine orange with DNA and RNA has been carried out. It was revealed that values of these parameters do not depend on nucleic acid type. It was shown that in the case of binding of each of these ligands to double-stranded (ds) DNA and ds-RNA the values of K and n are practically similar.

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Published

2017-11-13

How to Cite

Sahakyan, V.G. 2017. “EVALUATION OF BINDING PARAMETERS OF INTERCALATORS METHYLENE BLUE, ETHIDIUM BROMIDE AND ACRIDINE ORANGE WITH NUCLEIC ACIDS”. Proceedings of the YSU B: Chemical and Biological Sciences 51 (3 (244):176-78. https://doi.org/10.46991/PYSU:B/2017.51.3.176.

Issue

Vol. 51 No. 3 (244) (2017)

Section

Biology

License

Copyright (c) 2017 Proceedings of the YSU

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.