SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW DERIVATIVES OF 2-OXO-2,5-DIHYDROFURANS CONTAINING AN OXOTHIAZOLIDINYLIDENE RING

Authors

  • G.G. Tokmajyan Chair of Organic Chemistry, YSU, Armenia
  • L.V. Karapetyan Chair of Organic Chemistry, YSU, Armenia
  • R.V. Paronikyan Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences, Armenia
  • H.M. Stepanyan Scientific-Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences, Armenia

DOI:

https://doi.org/10.46991/PYSU:B/2020.54.1.012

Keywords:

3-acetyl-2-oxo-2,5-dihydrofurans, thiosemicarbazones, oxothiazolidinylidene ring synthesis, antibacterial activity

Abstract

ring were successfully synthesized based on thiosemicarbazones of 3-acetyl-2-oxo-2,5-dihydrofurans. The synthesized compounds exhibited moderate to defined antibacterial activities against Gram-positive (Staphylococcus aureus 209P and 1) and Gram-negative (Shigella Flexneri 6858, Esherichia coli 0–55) bacteria compared to furazolidone.

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Published

2020-04-15

How to Cite

Tokmajyan, G.G., L.V. Karapetyan, R.V. Paronikyan, and H.M. Stepanyan. 2020. “SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW DERIVATIVES OF 2-OXO-2,5-DIHYDROFURANS CONTAINING AN OXOTHIAZOLIDINYLIDENE RING”. Proceedings of the YSU B: Chemical and Biological Sciences 54 (1 (251):12-16. https://doi.org/10.46991/PYSU:B/2020.54.1.012.

Issue

Vol. 54 No. 1 (251) (2020)

Section

Chemistry

License

Copyright (c) 2020 Proceedings of the YSU

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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