SOME LAMIACEAE FAMILY PLANT ESSENTIAL OIL CHEMICAL COMPOSITION AND THEIR POTENTIAL AS ANTIMICROBIAL AGENTS AGAINST ANTIBIOTIC-RESISTANT BACTERIA
DOI:
https://doi.org/10.46991/PYSU:B/2019.53.1.023Keywords:
essential oils, antibiotic resistance, antibacterial activityAbstract
The antimicrobial activity of essential oils (EO) from several plants of Lamiaceae family (Ziziphora clinopodioides Lam., Thymus vulgaris L., Ocimum × citriodorum, O. basilicum var. purpureum, O. basilicum var. thyrsiflora, Origanum vulgare L.), spread in Armenia, was studied using agar diffusion method. As test-organisms the ampicillin-resistant Escherichia coli dp5α-pUC18 and non-resistant E. coli VKPM M-17 were used. Dimethyl sulfoxide was used as the solvent and negative control; gentamicin was applied as the positive control. O. × citriodorum, O. basilicum var. purpureum and T. vulgaris EO expressed the strongest activity against E. coli dpα-pUC18; minimal inhibitory concentrations (MIC) was 6.25 μL·mL–1. MIC of the O. basilicum var. thyrsiflora EO was 12.5 μL·mL–1. Z. clinopodioides and O. vulgare EO MIC was 50 μL·mL–1. Thus, EO from the Lamiaceae family plants could be recommended as antimicrobial agents against antibiotic-resistant bacteria.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Proceedings of the YSU
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.