THE INFLUENCE OF pH ON INTERACTION OF CuTOEPyP4 WITH DNA

Authors

  • Ye. B. Dalyan Chair of Molecular Physics, YSU, Armenia
  • I. V. Vardanyan Chair of Molecular Physics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:A/2008.42.3.097

Keywords:

Cu(II)-meso-tetra-(4N-hydroxyethylpyridyl)porphyrin, spectrophotometry, circular dichroism, constant of binding

Abstract

The interaction of Cu(II)-meso-tetra-(4N-hydroxyethylpyridyl)porphyrin (CuTOEPyP4) with DNA at different pH was studied by methods of spectrophotometry and circular dichroism. It was shown that these porphyrins bind to DNA preferably via intercalation. The calculations show that the constant of binding of CuTOEPyP4 with DNA strongly depend upon the pH.

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Published

2023-10-06

How to Cite

Dalyan, Y. B., & Vardanyan, I. V. (2023). THE INFLUENCE OF pH ON INTERACTION OF CuTOEPyP4 WITH DNA. Proceedings of the YSU A: Physical and Mathematical Sciences, 42(3 (217), 97–100. https://doi.org/10.46991/PYSU:A/2008.42.3.097

Issue

Section

Physics