THE INFLUENCE OF PERIPHERAL SUBSTITUENTS ON INTERACTION OF PORPHYRINS WITH DNA

Authors

  • L. R. Aloyan Chair of Molecular Physics, YSU, Armenia
  • G. V. Ananyan Chair of Molecular Physics, YSU, Armenia
  • V. I. Vardanyan Chair of Molecular Physics, YSU, Armenia
  • Ye. B. Dalyan Chair of Molecular Physics, YSU, Armenia

DOI:

https://doi.org/10.46991/PYSU:A/2006.40.3.040

Keywords:

meso-tetra-(3N-pyridyl)porphyrins, spectrophotometry, circular dichroism, binding constants, base pairs

Abstract

The interaction of meso-tetra-(3N-pyridyl)porphyrins with different peripheral substituents was studied by methods of spectrophotometry and circular dichroism. It was shown that for less concentration these porphyrins bind to DNA preferably via intercalation. The binding constants (Kb) and the number of binding sites per base pairs (n) were calculated by Correia and co-authors’ method.

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Published

2006-10-27

How to Cite

Aloyan, L. R., Ananyan, G. V., Vardanyan, V. I., & Dalyan, Y. B. (2006). THE INFLUENCE OF PERIPHERAL SUBSTITUENTS ON INTERACTION OF PORPHYRINS WITH DNA. Proceedings of the YSU A: Physical and Mathematical Sciences, 40(3 (211), 40–45. https://doi.org/10.46991/PYSU:A/2006.40.3.040

Issue

Section

Physics

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